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Intensive Care Med. 2003 Jul;29(7):1077-80. Epub 2003 May 13.
Risk factors of nosocomial catheter-associated urinary tract infection in a polyvalent intensive care unit.

Leone M, Albanese J, Garnier F, Sapin C, Barrau K, Bimar MC, Martin C.

Intensive Care Unit and Trauma Center, Nord Hospital AP-HM, Bd P. Dramard, 13915, Marseille, France. marc.leonp-hm.fr

OBJECTIVE: To determine the risk factors for catheter-associated urinary tract infection in a polyvalent intensive care unit (ICU). DESIGN: Prospective cohort study. SETTING: Sixteen-bed polyvalent ICU in a French university hospital. INTERVENTIONS: Prospective patient surveillance of patients included in two successive studies of two urine drainage systems. MAIN OUTCOME MEASURES: Bacteriuria occurrence in 553 ICU patients requiring a bladder catheter for longer than 48 h. The following variables were analyzed as possible risk factors: age, sex, severity score at admission, diagnosis on admission, duration of bladder catheterization, length of ICU stay, prior exposure to antibiotics, and system of urine drainage. RESULTS: The frequency of catheter-associated bacteriuria was 9.6%. From the multivariate analysis, five independent risk factors were determined: female sex, length of ICU stay, use of an antimicrobial therapy, severity score at admission, and duration of catheterization. CONCLUSION: In our study, the drainage system did not influence the occurrence of bacteriuria. To decrease the rate of catheter-associated bacteriuria in polyvalent ICU patients, removal of the bladder catheter must be performed as soon as possible.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12743682&dopt=Abstract [PubMed - in process]

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