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Eur J Dermatol. 2003 May-Jun;13(3):297-8.
Lipsch tz genital ulceration: a rare manifestation of paratyphoid fever.

Pelletier F, Aubin F, Puzenat E, Deprez P, Blanc D, Estavoyer JM, Humbert P.

Service de Dermatologie 1, Hopital Saint-Jacques, 2, place Saint-Jacques, 25030 Besancon cedex, France.

In 1913, a distinctive clinical entity of acute genital ulcer occurring in an adolescent girl with a non-venereal infectious aetiology was described by Lipsch tz. Since the initial description, several aetiologies have been discussed, and among them, paratyphoid fever is very uncommon. After her return from a trip, a 25-year-old girl developed high fever and diarrhoea. Examination of the vulva revealed a genital ulcer. The rest of the general examination was normal. Blood cultures identified Salmonella paratyphi A, and a diagnosis of Lipsch tz's ulcer associated with paratyphoid fever was made. Bacteriaemia was then treated with antibiotics and the vulvar ulceration rapidly disappeared. Lipsch tz described a distinctive clinical entity of acute genital ulcers occurring in adolescents. To our knowledge, we report herein the second case associated with proved paratyphoid fever. The authors thus recommend that typhoid or paratyphoid fever should be included in the differential diagnosis of genital ulcerations.

online pharmacy ref. source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12804994&dopt=Abstract [PubMed - in process]

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