Ionamin online research references
Toxicol Lett. 1984 Aug;22(2):133-8.
Alterations in monoamine oxidase activity after single and repeated exposure of rats to chlorphentermine.
Zychlinski L, Montgomery MR.
Monoamine oxidase (MAO) activity was determined in rat tissues following in vivo treatments with chlorphentermine (CP). Oxidation of seven amine substrates by liver, lung or brain mitochondrial MAO was investigated at 2 h after a single i.p. injection (60 mg/kg) or after repeated injection (once daily for 3 days, 20 mg/kg, i.p.). Deamination of the type A substrates, norepinephrine, serotonin and octopamine, was decreased significantly in liver, lung and brain after both single and repeated injections. Oxidative deamination of tyramine and dopamine (type A + B substrates) was also lowered in all organs after single and repeated exposure to CP, but to a lesser degree than the type A substrates. However, oxidation of the type B substrates, benzylamine and tryptamine, was unaffected by CP administration in comparison to control. These data indicate that CP is a specific inhibitor of mitochondrial MAO, form A.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6474505&dopt=Abstract
kwd match ionamin online literature
Life Sci. 1984 Sep 17;35(12):1297-300.
The ability of certain anorexic drugs to suppress food consumption depends on the nutrient composition of the test diet.
Moses PL, Wurtman RJ.
The effects of five anorexic agents on food consumption were tested in rats offered single, isocaloric, isonitrogenous diets differing in carbohydrate content. Three of the test agents, d-amphetamine, benzphetamine and chlorphentermine, are sympathomimetic and cause CNS stimulation; the others, MK-212 and d-fenfluramine, are thought to facilitate serotonin-mediated neurotransmission. At ED50 doses, the sympathomimetic drugs reduced food consumption whether the test diet was rich (75% dextrin) or poor (25% dextrin) in carbohydrate. In contrast, MK-212 and d-fenfluramine failed to reduce consumption of the 25% dextrin test diet. These observations suggest that anorexic drugs like d-amphetamine and d-fenfluramine do not act via a common "amphetamine receptor," and are compatible with earlier observations, made on rats given diet pairs simultaneously, that enhanced serotoninergic neurotransmission selectively suppresses appetite for carbohydrates.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6482653&dopt=Abstract
kwd match ionamin online literature
Zentralbl Gynakol. 1978;100(4):217-21.
[Suitability of mephentermine for the management of arterial hypotension in pregnancy]
[Article in German]
Lauckner W, Schwarz R, Retzke U.
10 late pregnant women with hypotension were examined before and after the intravenous injection of 30 mg mephentermin with the method of quantitative sphygmometry, the bloodless graphic registration of the arterial blood pressure and direct electronic timing of pulse wave velocity. Systolic and diastolic blood pressure increase significantly. The cause of this rise in arterial blood pressure is the increase of stroke volume exclusively. Heart rate and total peripheral resistance remain constant. This hemodynamic mode of action is a favourable one in regard to protection of uteroplacental blood flow. Therefore mephentermin is suitable for treatment of hypotension in pregnancy.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=654658&dopt=Abstract
kwd match ionamin online literature
Dream Pharmaceuticals Rx Online Bontril
Dream Pharmaceuticals Rx Online Celebrex
Dream Pharmaceuticals Rx Online Evista
DreamPharm: Herbal and Nutritional supplements online ||
Hair Million herbal formula for hair loss and hair growth ||
Dream Pharmaceuticals Rx: Prescription Drugs Online || Tramadol Online || Paxil Online || Buspar Online || Cialis Online || Antibiotics Online
Antibiotics and prescription medications online literature ||
E-Mail Us