Tramadol References
Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol.
Enantiomeric separation of tramadol hydrochloride and its metabolites by cyclodextrin-mediated capillary zone electrophoresis.
Treatment of pain with sustained-release tramadol 100, 150, 200 mg: results of a post-marketing surveillance study.
Tramadol reduces the sweating, vasoconstriction, and shivering thresholds.
Use of tramal for prevention of motor hyperactivity during r fiber bronchoscopy in patients in the postoperative period
Tramadol induces antidepressant-type effects in mice.
Simultaneous stereoselective analysis of tramadol and its main phase I metabolites by on-line capillary zone electrophoresis-electrospray ionization mass spectrometry.
Synthesis and analgesic activity of some quinazoline analogs of anpirtoline.
The antinociceptive effect of tramadol on a model of neuropathic pain in rats.
Direct tramadol application on sciatic nerve inhibits spinal somatosensory evoked potentials in rats.
Pain in elderly patients and aspects of its therapy
Ketoprofen (ketonal): a drug for preventing and treating postoperative pain
Complications and adverse effects of colonoscopy with selective sedation.
Tramadol in the treatment of pain
Gas chromatographic method using nitrogen-phosphorus detection for the measurement of tramadol and its O-desmethyl metabolite in plasma and brain tissue of mice and rats.
research_abstConcordance between tramadol and dextromethorphan parent/metabolite ratios: the influence of CYP2D6 and non-CYP2D6 pathways on biotransformation.
Labelling studies for structure elucidation of a new hydroxymetabolite of tramadol.
Direct chiral assay of tramadol and detection of the phase II metabolite O-demethyl tramadol glucuronide in human urine using capillary electrophoresis with laser-induced native fluorescence detection.
Tramadol has no effect on cortical renal blood flow--despite increased serum catecholamine levels--in anesthetized rats: implications for analgesia in renal insufficiency.
Influence of oral tramadol on the dynamic ventilatory response to carbon dioxide in healthy volunteers.
Comparison of nerve conduction blocks by an opioid and a local anesthetic.
Isobolographic analysis of the analgesic interactions between ketamine and tramadol.
Effect of acute and chronic tramadol on 3H-norepinephrine-uptake in rat cortical synaptosomes.
The antinociceptive effect of tramadol in the formalin test is mediated by the serotonergic component.
The analgesic drug tramadol prevents the effect of surgery on natural killer cell activity and metastatic colonization in rats.
Selegiline: a second look. Six years later: too risky in Parkinson's disease.
The inhibitory effects of tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M(3) receptors.
Actions of drugs affecting the cough reflex
research_abstTramadol reduces the 5-HTP-induced head-twitch response in mice via the activation of mu and kappa opioid receptors.
Effect of droperidol and tramadol combination on the hemostasis in rabbits
Pharmacokinetic/pharmacodynamic modeling of the antinociceptive effects of (+)-tramadol in the rat: role of cytochrome P450 2D activity.
Postoperative analgesia with tramal in newborn children using the method of continuous intravenous infusion
Pharmacokinetics of oral tramadol drops for postoperative pain relief in children aged 4 to 7 years--a pilot study.
Palliative care in a national cancer center: results in 1987 vs. 1993 vs. 2000.
Post-surgical paediatric pain: Nursing- PCA vs continuous I.V. infusion of tramadol
Switching opioids to transdermal fentanyl in a clinical setting
Actions of tramadol on micturition in awake, freely moving rats.
Microencapsulation and characterization of tramadol-resin complexes.
Withdrawal syndrome and dependence: tramadol too.
Lornoxicam, a new potent NSAID with an improved tolerability profile.
Development of electrochemical methods for determination of tramadol--analytical application to pharmaceutical dosage forms.
HPLC method for determination of tramadol hydrochloride in human plasma
Influence of complex solubility on formulations based on lambda carrageenan and basic drugs.
Interaction between metamizol and tramadol in a model of acute visceral pain in rats.
Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an 'atypical' opioid analgesic.
Evidence for a noradrenergic component in the antinociceptive effect of the analgesic agent tramadol in an animal model of clinical pain, the arthritic rat.
Clinical aspects of the use of nubain, tramal and moradol in patients in the early postoperative period
Effects of tramadol on rat detrusor overactivity induced by experimental cerebral infarction.
Pharmacokinetic-pharmacodynamic modeling of the antinociceptive effects of main active metabolites of tramadol, (+)-O-desmethyltramadol and (-)-O-desmethyltramadol, in rats.
Stereoselectivity in biliary excretion of trans tramadol and trans O-demethyltramadol in rats
Stapled hemorrhoidectomy for the treatment of hemorrhoids.
research_abstresearch_abstNon-steroidal anti-inflammatory drugs antagonise the constipating effects of tramadol.
The use of intraarticular tramadol for postoperative analgesia after arthroscopic knee surgery: a comparison of different intraarticular and intravenous doses.
research_abstTramadol versus buprenorphine for the treatment of opiate withdrawal: a retrospective cohort control study.
The use of tramadol for acute heroin withdrawal: a comparison to clonidine.
Combined general and epidural anesthesia with ropivacaine for renal transplantation.
Incidence of first-time idiopathic seizures in users of tramadol.
Introduction: Methods, Commentary, and Summary.
Tramadol--a multimodal, multipurpose analgesic for the surgeon.
Sentinel node biopsy in melanoma of the trunk and the extremities in tumescent local anesthesia.
Arousal in various analgosedation schedules
Relationship between the antitussic and analgesic activity of substances.
The use of tramal in the orthopedics-traumatology clinic
Postoperative patient-controlled analgesia with tramadol: analgesic efficacy and minimum effective concentrations.
The use of tramadol hydrochloride in the treatment of post-anesthetic shivering.
Dose- and time-dependent action of morphine, tramadol and flupirtine as studied by radioelectroencephalography in the freely behaving rat.
Diffusion of new drugs in Danish general practice.
Anticonvulsant and proconvulsant effects of tramadol, its enantiomers and its M1 metabolite in the rat kindling model of epilepsy.
Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids.
General pharmacological studies on tramadol, a potent analgetic agent
Effects of tramadol on motor and sensory responses of the spinal nociceptive system in the rat.
Effect of analgesic drugs on the electromyographic activity of the gastrointestinal tract and sphincter of Oddi and on biliary pressure.
Tramadol infusion anesthesia with the substitution of enflurane and various nitrous oxide concentrations
The therapeutic system, CODIC
Algo-pupillometric investigation of the analgesic effect of tramadol
Control of cancer pain with analgesics acting in the central nervous system.
Characterization of the effect of analgesics on the assessment of experimental pain in man. Pethidine and tramadol in a double-blind comparison
Automated sample preparation techniques for the determination of drug enantiomers in biological fluids using liquid chromatography with chiral stationary phases.
Effects of opioid analgesics on potential-gated ion channels in the pond snail neurons
The use of tramadol-HCl (Tramal) as adjuvant in regional anaesthesia. Clinical report
Infusion-controlled Tramal-anaesthesia
Neurophysiologic analysis of the effects of the centrally acting analgesics moradol, tramal and nubain
Comparative analysis of different premedication methods in minor surgery in children
A clinical-experimental study of narcotic properties of opiate receptor agonists-antagonists and experience in their use in drug addiction practice
Conservative and interventional therapy of chronic pancreatitis
Tramadol: new preparation. Capsules: central analgesic; step 2 on the WHO scale.
Immunity state of oncological patients during long-term treatment with tramal
Complementary and synergistic antinociceptive interaction between the enantiomers of tramadol.
Patient-controlled analgesia (PCA) for postoperative pain relief. A prospective observational study for evaluating the technology in a ward routine
Pindolol, a beta-adrenoceptor blocker/5-hydroxytryptamine(1A/1B) antagonist, enhances the analgesic effect of tramadol.
Effect of thiamine and riboflavin derivatives on the activity of xenobiotic-metabolizing enzyme and on the pharmacologic effect of analgesics
Postoperative analgesia
Unexpected antinociceptive effect of the N-oxide (RWJ 38705) of tramadol hydrochloride.
Influence of tramadol on neurotransmitter systems of the rat brain.
Tramadol, M1 metabolite and enantiomer affinities for cloned human opioid receptors expressed in transfected HN9.10 neuroblastoma cells.
The antinociceptive effect of tramal when combined with nonsteroidal anti-inflammatory preparations
How we use opioid drugs on patients with neoplasms
Role of epidural tramadol hydrochloride on postoperative pain relief in caesarean section delivery.
Actions of tramadol, its enantiomers and principal metabolite, O-desmethyltramadol, on serotonin (5-HT) efflux and uptake in the rat dorsal raphe nucleus.
Kinetics of tramal, benzofurocain and amidopyridine demethylation under inhibitory conditions produced by cimetidin, orthophen and thiamine diphosphate
Achiral and chiral determination of tramadol and its metabolites in urine by capillary electrophoresis.
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